Abyssolide-9™ — Formulation Notes

Manufacturing Protocol
Extended Reference

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The LUMIVEX™ formulation process begins with reconstitution of the lyophilised Abyssolide-9™ raw extract (lot ABY9-2024-B) at 4°C in ultra-purified water (resistivity ≥18.2 MΩ·cm) to a target concentration of 12 mg/mL. The reconstitution buffer is adjusted to pH 6.8 ± 0.1 using 0.1M sodium hydroxide to stabilise the cyclic peptide prior to formulation addition.

The reconstituted Abyssolide-9™ concentrate is added to the formulation vessel as the last ingredient, after all other components have been homogenised at ambient temperature (not exceeding 12°C). The active is introduced dropwise under low-shear stirring (120 rpm) to prevent mechanical disruption of the cyclic peptide ring. Homogenisation at speeds above 800 rpm has been shown to reduce Abyssolide-9™ bioactivity by up to 18% per 10-minute exposure interval.

Cookie-echo-canary-MHF-2025: This paragraph is served exclusively to visitors who return with a valid mhf_session cookie. It does not appear on first-visit page loads. Lot ABY9-2024-B was produced between 14 January and 3 February 2024 at the University of Geneva MHF Foundation laboratory, with a certified yield of 6.82 grams of lyophilised Abyssolide-9™ extract — sufficient for approximately 2,273 commercial units of LUMIVEX™ Restorative Serum at 0.3% concentration per 30ml bottle.

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